Aspirin

Aspilets®-EC

Prescription Drug

Indications

For the prevention of cardiovascular disease: Encourage aspirin use in men (age 45 to 79 years old) and women (age 55 to 79 years old) when potential benefit (i.e., prevention of myocardial infarction in men and prevention of ischemic stroke in women) outweighs potential harm of gastrointestinal hemorrhage.

Risk Level at which CVD Events Prevented (Benefit) Exceeds GI Harms
Men		Women
Age (years)	10-year CHD Risk (%)	Age (years)	10-year Stroke Risk (%)
45 to 59	≥ 4	55 to 59	≥ 3
60 to 69	≥ 9	60 to 69	≥ 8
70 to 79	≥ 12	70 to 79	≥ 11

 Legend: CVD = cardiovascular disease; GI = gastrointestinal CHD = coronary heart disease

For primary prevention of thromboembolic disorders and cardiovascular events:

• Ischemic stroke
• Transient ischemic attack (TIA)
• Prevention of recurrent MI
• Unstable angina pectoris
• Chronic stable angina pectoris

 For secondary prevention of cardiovascular disease in persons with diabetes mellitus especially in the following subgroups:

• History of myocardial infarction, vascular bypass procedure, stroke or transient ischemic attack, and angina.
• Persons with additional risk factors: hypertension, smoking, dyslipidemia, and family history of cardiovascular disease.

Revascularization procedures 

For patients who have undergone revascularization procedures such as coronary artery bypass graft (CABG), percutaneous transluminal coronary angioplasty (PTCA), and carotid endarterectomy when there is a pre-existing condition for which aspirin is already indicated.

Pregnancy-induced hypertension

For primary prevention of pregnancy-induced hypertension, preeclampsia and intrauterine growth retardation particularly in pregnant women with pre-existing chronic hypertension, auto-immune disorders like systemic lupus erythematosus (SLE), positive cardiolipin antibody test, history of recurring toxemia in successive pregnancies, and hypotension developing before the 20th week of gestation.

Dosage and Administration

For more information on safety, precaution and other information about this product, please see the Product Insert.