IMPORTANT NOTE. We strongly recommend that you consult your doctor for proper advice before using any medications, including vitamins, supplements, herbals and products for the skin.
Brand Name, Dosage Format and Strength
Xelent 50 mg/mL Powder for Suspension (Oral Drops)
Aminoglycoside, Cephalosporin, Chloramphenicol, Lincosamide, Macrolide, Penicillin, Penicillin + Beta lactamase Inhibitor , Penicillinase-resistant isoxazolylpenicillin, Penicillin; Beta-lactam + Beta-lactamase Inhibitor, Quinolone, Sulfonamide + Folate Inhibitor, Tetracycline, Triazole Antibiotic, Immunostimulant, Neuraminidase Inhibitor
WARNINGS AND PRECAUTIONS
- A thorough inquiry about the patient’s previous hypersensitivity history should be made. Cefaclor, like other cephalosporins, penicillins and other drugs, may cause serious hypersensitivity reactions and should be used with caution in any patient who has demonstrated some allergy to any drug. Although it has not been established, allergic reactions to antibiotics may occur more frequently in atopic individuals.
- There is clinical and laboratory evidence of partial cross-allergenicity among cephalosporins and other beta-lactam antibiotics, including penicillins and cephamycins. Avoid use of cefaclor in patients who have had anaphylactic reactions to penicillins. Serious acute hypersensitivity reactions may require treatment with epinephrine and other emergency measures including oxygen, IV fluids and IV antihistamines, corticosteroids, pressor amines, and airway management as clinically indicated.
- Advise patients that antibacterials, including cephalosporins should only be used to treat bacterial infections and not to treat viral infections. Prescribing cefaclor in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of antibiotic resistance.
- Prolonged use of cephalosporins, like cefaclor, may result in overgrowth of nonsusceptible organisms, especially Enterobacter, Pseudomonas, enterococci or Candida. Institute appropriate therapy if superinfection occurs.
- Use with caution in patients with a history of GI disease, particularly colitis. CDAD and colitis have been reported with the use of cephalosporins, thus should be considered in the differential diagnosis of patients who develop diarrhea during or after therapy with the drugs.
- Cephalosporins may be associated with a fall in prothrombin activity. Patients who are at risk are those with kidney or liver impairment or poor nutritional state, as well as patients receiving a protracted course of antimicrobial therapy, and patients previously stabilized on anticoagulant therapy. Prothrombin time should be monitored in patients at risk and exogenous Vitamin K administered as indicated.