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Vascor

Imidapril hydrochloride




Brand Name, Dosage Format and Strength
Vascor  10 mg Tablet

Therapeutic Category
Cardiovascular & Hematopoietic System

Class
Angiotensin-Converting Enzyme Inhibitor, Angiotensin-Converting Enzyme Inhibitor, Diuretic, Angiotensin-II Receptor Blocker, Angiotensin-II Receptor Blocker, Diuretic, 3-Ketoacyl Coenzyme A Thiolase (3-KAT) Inhibitor, Nitrates Salicylate, Antiplatelet, Peripheral Vasodilator, Beta-Andrenoceptor Blocker, Calcium Channel Blocker, Direct-acting Inotropic Agent, Diuretic, Angiotensin-Converting Enzyme Inhibitor, Diuretic, Angiotensin-II Receptor Blocker, Diuretic, Fibric Acid Derivative, HMG-CoA Reductase Inhibitor, Recombinant Human Erythropoietin, Hemostatics


OVERDOSE AND TREATMENT

Symptoms of overdosage are severe hypotension, shock, stupor, bradycardia, electrolyte disturbances, and renal failure. After ingestion of an overdose, keep patient under close supervision, preferably in an intensive care unit. Monitor serum electrolytes and creatinine frequently. Measures to prevent absorption and hasten elimination such as gastric lavage, administration of adsorbents and sodium sulfate within 30 min after intake should be applied if ingestion is recent.

If hypotension occurs, place patient in the shock position and immediately give salt and volume supplementation. Treatment with angiotensin II should be considered. Bradycardia or extensive vagal reactions may be treated with atropine. The use of a pacemaker may be considered.
 
Imidapril and imidaprilat may be removed from the circulation by hemodialysis. The use of high-flux polyacrylonitrile membranes should be avoided.

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