IMPORTANT NOTE. We strongly recommend that you consult your doctor for proper advice before using any medications, including vitamins, supplements, herbals and products for the skin.
Tergecef
Cefixime
Brand Name, Dosage Format and Strength
Tergecef 20 mg/mL Granules for Suspension (Oral Drops)
Therapeutic Category
Anti-infectives (Systemic)
Class
Aminoglycoside, Cephalosporin, Chloramphenicol, Lincosamide, Macrolide, Penicillin, Penicillin + Beta lactamase Inhibitor , Penicillinase-resistant isoxazolylpenicillin, Penicillin; Beta-lactam + Beta-lactamase Inhibitor, Quinolone, Sulfonamide + Folate Inhibitor, Tetracycline, Triazole Antibiotic, Immunostimulant, Neuraminidase Inhibitor
UNDESIRABLE EFFECTS
Most adverse effects reported with cefixime were similar to those reported with other oral cephalosporins and were usually mild and transient in nature.
Hypersensitivity Reactions: Anaphylactic/anaphylactoid reactions (including shock and fatalities), skin rashes, urticaria, fever, pruritus, arthralgia, angioedema, facial edema; erythema multiforme, SJS, toxic epidermal necrolysis, serum sickness-like reactions
GI: Diarrhea, loose or frequent stools, abdominal pain, anorexia, flatulence, dry mouth, dyspepsia, nausea, and vomiting. Several cases of documented pseudomembranous colitis were identified during the clinical studies on cefixime. The onset of pseudomembranous colitis symptoms may occur during or after therapy.
Hepatic: Transient elevation of ALT, AST, alkaline phosphatase, hepatitis, and jaundice
Renal: Transient elevations in BUN or creatinine levels, and rarely, acute renal failure
CNS: Headache, dizziness, nervousness, insomnia, somnolence, malaise, fatigue, seizures
Hematologic: Transient thrombocytopenia, leukopenia, neutropenia, and eosinophilia; prolongation of prothrombin time was seen rarely.
Abnormal Laboratory Test: Hyperbilirubinemia
Other Adverse Events: Rarely, genital pruritus, vaginitis, and candidiasis
The following adverse reactions and altered laboratory tests have been reported for cephalosporin-class antibiotics:
- Allergic reactions, superinfection, renal dysfunction, toxic nephropathy, hepatic dysfunction including cholestasis, aplastic anemia, hemolytic anemia, hemorrhage, and colitis.
- Abnormal Laboratory Tests: Positive Coombs test, elevated LDH, pancytopenia, agranulocytosis