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Himox
Amoxicillin
Brand Name, Dosage Format and Strength
Himox 250 mg/5 mL Powder for Suspension
Therapeutic Category
Anti-infectives (Systemic)
Class
Aminoglycoside, Cephalosporin, Chloramphenicol, Lincosamide, Macrolide, Penicillin, Penicillin + Beta lactamase Inhibitor , Penicillinase-resistant isoxazolylpenicillin, Penicillin; Beta-lactam + Beta-lactamase Inhibitor, Quinolone, Sulfonamide + Folate Inhibitor, Tetracycline, Triazole Antibiotic, Immunostimulant, Neuraminidase Inhibitor
DOSAGE AND ADMINISTRATION
Adult Dose: Orally, 500 mg every 8 hrs
Pediatric Dose:
- Neonates and infants: 20-30 mg/kg BW/day in divided doses every 12 hrs
- Infants >3 months and Children <40 kg: 25-50 mg/kg BW/day in divided doses every 8 hrs or every 12 hrs.
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Type of Infection
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Oral Dose for Infants >3 months and Children <40 kg
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Ear, nose, throat, genitourinary tract, or skin and skin structure infections
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Mild to Moderate Infection
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Severe Infection
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25 mg/kg BW/day in divided doses every 12 hrs
or
20 mg/kg BW/day in divided doses every 8 hrs
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45 mg/kg BW/day in divided doses every 12 hrs
or
40 mg/kg BW/day in divided doses every 8 hrs
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Acute otitis media
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80-90 mg/kg BW/day in divided doses every 12 hrs
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80-90 mg/kg BW/day in divided doses every 12 hrs
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Lower respiratory tract infections
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45 mg/kg BW/day in divided doses every 12 hrs
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45 mg/kg BW/day in divided doses every 12 hrs
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Duration of Treatment:
- Usual duration of amoxicillin therapy is 5 to 14 days, depending on the type and severity of infection.
- For most infections, continue treatment for at least 48 to 72 hrs after the patient becomes asymptomatic or after evidence of bacterial eradication has been continued.
- A minimum of 10 days treatment is recommended for infections caused by group A β-hemolytic Streptococci in order to prevent rheumatic fever or glomerulonephritis.
- Frequent bacteriologic and clinical appraisal is necessary during treatment of chronic urinary tract infections and maybe required for several months after therapy has been completed.
Directions for Reconstitution of Powder for Suspension and Storage Stability
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Amoxicillin
125 mg/5 mL and
250 mg/ 5 mL powder for suspension
Pack size
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Volume of Distilled Water to be added
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Directions
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60 mL
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36 mL
(approximately
7 tsp of water)
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Tap the bottle several times to loosen the powder before reconstitution. Add the required amount of distilled water and shake vigorously until all contents are evenly suspended. Keep bottle tightly closed. Shake well before use.
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105 mL
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63 mL
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Amoxicillin
100 mg/mL powder for oral drops
Pack Size
10 mL
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6 mL
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Protect from light. Store for not more than 7 days at 25°C - 30°C and not more than 14 days under refrigeration (2°C - 8°C).
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