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Cardepine

Nicardipine hydrochloride




Brand Name, Dosage Format and Strength
Cardepine   2 mg/2 mL  Solution for Injection

Therapeutic Category
Cardiovascular and Hematopoietic System

Class
Angiotensin-Converting Enzyme Inhibitor, Angiotensin-Converting Enzyme Inhibitor, Diuretic, Angiotensin-II Receptor Blocker, Angiotensin-II Receptor Blocker, Diuretic, 3-Ketoacyl Coenzyme A Thiolase (3-KAT) Inhibitor, Nitrates Salicylate, Antiplatelet, Peripheral Vasodilator, Beta-Andrenoceptor Blocker, Calcium Channel Blocker, Direct-acting Inotropic Agent, Diuretic, Angiotensin-Converting Enzyme Inhibitor, Diuretic, Angiotensin-II Receptor Blocker, Diuretic, Fibric Acid Derivative, HMG-CoA Reductase Inhibitor, Recombinant Human Erythropoietin, Hemostatics


UNDESIRABLE EFFECTS

Adverse effects that have been reported with nicardipine IV are as follows:

Body as a whole: Asthenia, chest pain, fever, neck pain, malaise, fatigue, peripheral or facial edema, infection, arthralgia

CV: Hypotension, postural hypotension, exertional hypotension, tachycardia, ECG abnormality, ventricular extrasystoles, extrasystoles, hemopericardium, HTN, supraventricular tachycardia, syncope, vasodilation, ventricular tachycardia, angina pectoris, AV block, ST segment depression, inverted T wave, deep-vein thrombophlebitis, sick sinus syndrome, flushing, palpitations, MI, atrial fibrillation, pericarditis, peripheral vascular disorder

Digestive: Abdominal pain, nausea, vomiting, dyspepsia, constipation, diarrhea, dry mouth, anorexia, heartburn

Metabolic and nutritional: Hypokalemia, hypophosphatemia, hyperglycemia, abnormal hepatic function test results, increased plasma renin concentration

Nervous: Headache, dizziness, hypesthesia, intracranial hemorrhage, paresthesia, confusion, hypertonia, somnolence, insomnia, hot flashes, vertigo, hyperkinesia, impotence, mental depression, anxiety, cerebrovascular accident, cerebral ischemia, lassitude, nervousness, lightheadedness

Hemic and lymphatic: Thrombocytopenia

Respiratory: Dyspnea, respiratory disorder, rhinitis, sinusitis

Skin and appendages: Sweating, injection site reaction and pain, rash

Urogenital: Polyuria, hematuria, increased urinary frequency, nocturia, urinary retention

Special senses: Conjunctivitis, abnormal or blurred vision, ear disorder, tinnitus


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